Sirtuin Mimicry: vastly more powerful than resveratrol

I’m going to run with FuturePundit‘s take on this one, though it’s been bouncing around a couple days earlier.

This is seriously exciting stuff.  Diabetes is ripping a gigantic hole in our society’s longevity, so even if it’s only approved as a “keep the weight down and diabetes at bay” prescription-only critter, it’s a big step forward.

Otherwise, if the next drug is indeed much more powerful than the one they’ve already been testing (which makes resveratrol look like junk by comparison)… the possibilities boggle.

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  1. Wait; I thought that the affect they’re discussing didn’t really work in humans?

  2. Alex

     /  November 5, 2008

    Turn on the metabolism in the right way and it will work in humans. My concern is if the metabolism switches back off at all. They deliberately fed the mouse a high fat diet, so what happens when you limit the food intake back to normal? Does the accelerated metabolism start to metabolize muscle and other tissue? Presumably though the body would use up this particular molecule which turns the metabolism from normal to fast, and in the absence of this molecule the metabolism goes back to normal.

    Presumably though.

  3. Welcome to your 6kcalorie-per-day-or-else diet?


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