Longsuffering Wife and I  are both mildly allergic to wasps and bees.  So, while I personally like them, and always have, I’ve been keeping them off the garage where they might make a larger than normal nest.  If you want to take out a hornet nest, or a wasp nest, I now have one absolute recommendation:

1 Squirt bottle

1 pint undiluted orange oil

They can’t retaliate if they can’t track you, and, for creatures for whom smell is more “real” than vision, they can’t do that if they’ve just had the equivalent of a sulfuric acid bath sprayed all over them.